Omega
July 8, 2026

What are endo-cannabinoids? And why should you care as a daily stoner?

Keep reading and you may change your diet forever. For the better! By the end of this article you’ll understand the brain biology of weed better than 99% of daily smokers.

When you find out which food contains natural endo-cannabinoids, you’ll appreciate the genius of mother nature and the marijuana plant more than ever.

Here’s how cannabis works

Cannabis works when the THC in cannabis activates a receptor in your brain called cannabinoid B1 (Aka CB1). THC goes into the CB1 receptor and then you experience the feelings of being high on pot.

Summary: THC + THC receptor (CB1) = cannabis high

But have you ever wondered what normally activates the same receptor as THC?

The receptor was not sitting around waiting for your hairless-monkey ass to light the bud of a cannabis plant on fire and inhale it.

No.

The THC receptor is naturally activated by something other than THC.

En-do-cann-ab -in-oids (Endo-cannabinoids)

(Six whole syllables. 16 letters! I know. In 2026. Bro?!)

The natural something that activates the same receptor as THC is called an endo-cannabinoid.

Endo means “within”. Cannabinoid means something that activates the CB1 receptor.

So endo-cannabinoid means something that comes from within that activates the CB1 receptor.

In contrast, THC is called an exogenous-cannabinoid. Exogenous means from outside.

THC is also called a phyto-cannabinoid. Phyto means plant. So phyto-cannabinoid means a cannabinoid that comes from a plant.

THC is not an endo-cannabinoid though because It does not come from within.

So what are your natural cannabinoids? What are endo-cannabinoids?

Omegas!

The answer to “What are endo-cannabinoids?” is hiding in plain sight. Guess what is FULL of endo-cannabinoids?

Hemp seed oil.

Omega-3 and omega-6s are natural endo-cannabinoids.

Your body turns Omega-3s and omega-6s into endocannabinoids after you eat them.

Hemp seed oil is full of plant omega-3s. Plant and animal omega-3s are different. (But that’s another blog.)

Omega-3s help keep your brain and endo-cannabinoid system working well and in balance. Balance doesn’t sound sexy until you consider an unbalanced mind.

An unbalanced endo-cannabinoid system has a high tolerance.

An unbalanced and “exhausted” endocannbinoid system leads to brain fog.

An unbalanced and exhausted endocannabinoid system leads to a bad memory.

How omega-3s help

Omega-3s are endo-cannabinoids.

Omega-3s support your cognitive health and brain function. Omega-3s do this in part through your endo-cannabinoid system.

This is why cannabis users should be taking a high dose omega-3 supplement like omega trees daily.

Improve your health and how you feel.

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Michael Barr
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